Network Pharmacology-Based Prediction of Catalpol and Mechanisms against Stroke

Table 2

Results of KEGG enrichment analysis.

	Term	Pathway	Genes
Cancer	cfa05205	Proteoglycans in cancer	MAPK1, MAP2K1, MAPK14, MMP9, IGF1, PLAU, KDR, TGFB2
	cfa05200	Pathways in cancer	MAPK1, MAP2K1, PGF, MMP9, PPARG, IGF1, NOS2, TGFB2
	cfa05216	Thyroid cancer	MAPK1, MAP2K1, PPARG
	cfa04014	Ras signaling pathway	MAPK1, MAP2K1, PGF, IGF1, KDR
	cfa04668	TNF signaling pathway	MAPK1, MAP2K1, MAPK14, MMP9
Parasitic disease	cfa05140	Leishmaniasis	MAPK1, MAPK14, JAK2, NOS2, TGFB2
	cfa05142	Chagas disease (American trypanosomiasis)	MAPK1, ACE, MAPK14, NOS2, TGFB2
	cfa05145	Toxoplasmosis	MAPK1, MAPK14, JAK2, NOS2, TGFB2
Angiogenesis remodeling	cfa04370	VEGF signaling pathway	MAPK1, MAP2K1, MAPK14, MAPKAPK2, KDR
	cfa04068	FoxO signaling pathway	MAPK1, MAP2K1, MAPK14, IGF1, SOD2, TGFB2
	cfa05152	Tuberculosis	MAPK1, VDR, MAPK14, JAK2, NOS2, TGFB2
	cfa04015	Rap1 signaling pathway	MAPK1, MAP2K1, PGF, MAPK14, IGF1, KDR
	cfa04380	Osteoclast differentiation	MAPK1, MAP2K1, MAPK14, PPARG, TGFB2
	cfa04917	Prolactin signaling pathway	MAPK1, MAP2K1, MAPK14, JAK2
	cfa04914	Progesterone-mediated oocyte maturation	MAPK1, MAP2K1, MAPK14, IGF1
	cfa04066	HIF-1 signaling pathway	MAPK1, MAP2K1, IGF1, NOS2
Inflammation, cancer	cfa04668	TNF signaling pathway	MAPK1, MAP2K1, MAPK14, MMP9
	cfa04151	PI3K-Akt signaling pathway	MAPK1, MAP2K1, PGF, IGF1, JAK2, KDR
Axonal growth nerve remodeling	cfa04722	Neurotrophin signaling pathway	MAPK1, MAP2K1, MAPK14, MAPKAPK2
	cfa04550	Signaling pathways regulating pluripotency of stem cells	MAPK1, MAP2K1, MAPK14, IGF1, JAK2
Cell growth, barrier	cfa04510	Focal adhesion	MAPK1, MAP2K1, PGF, IGF1, KDR