Traditional Chinese Medicine <i>Yang-Gan-Wan</i> Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models

<div>Oral YGW treatment effectively alleviated apoptosis in the liver tissue of APAP-treated mice. (a) IHC staining showed the expression of the apoptosis-related marker c-caspase 3 in the liver tissue of sham-treated mice and APAP-treated mice after NAC, pre-YGW, post-YGW, and pre- and post-YGW treatments. Scale bar = 30 <i>μ</i>m. (b) c-caspase 3/caspase 3 expression was significantly higher in the liver tissue of APAP-treated mice than in that of APAP-treated mice after NAC, pre-YGW, post-YGW, and pre- and post-YGW treatments (<i>n</i> = 3 for each group; values are presented as mean ± SEM).</div>

Evidence-Based Complementary and Alternative Medicine

fig10

Figure 10

Figure 10: Traditional Chinese Medicine <i>Yang-Gan-Wan</i> Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models 

Figure 10 | Traditional Chinese Medicine Yang-Gan-Wan Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models 