Traditional Chinese Medicine <i>Yang-Gan-Wan</i> Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models

<div>YGW treatments effectively alleviated LPS-induced damage in Kupffer cells. (a) Damaged and elongated Kupffer cells (indicated by the arrow) were observed after treatment with 1 <i>μ</i>g/mL LPS; their morphology was restored to normal after treatment with 15 mg/mL YGW for 24 and 72 h scale bar = 30 <i>μ</i>m. (b) MTT assay showed the cell viability of liver Kupffer cells under different concentrations of YGW. Irrespective of LPS treatment, the viability of Kupffer cells treated with YGW (5–20 mg/mL) significantly increased compared with that of Kupffer cells not treated with YGW (<i>n</i> = 3 for each group; values are presented as mean ± SEM).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: Traditional Chinese Medicine <i>Yang-Gan-Wan</i> Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models 

Figure 3 | Traditional Chinese Medicine Yang-Gan-Wan Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models 