Antihypertensive Effects of the Methanol Extract and the Ethyl Acetate Fraction from Crinum zeylanicum (Amaryllidaceae) Leaves in L-NAME-Treated Rat

Figure 3

Repeated administration of the methanol extract and the ethyl acetate fraction from the leaves of Crinum zeylanicum time-dependently reduced systolic blood pressure in rats treated with L-NAME; 6 ≤ n ≤ 8. Analysis was done with ANOVA two-way followed by Bonferroni posttest (panels A and C) or ANOVA one-way followed by Tukey posttest (panels B and D). , , and : significant difference as compared to the naive group. : significant difference as compared to L-NAME treated group. , , and : significant difference between concerned groups. Capto20: captopril, LME: leaves methanol extract, LEAF: leaves ethyl acetate fraction, SBP: systolic blood pressure, and naive: normal untreated animals.

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