| Study ID | Disease | Sample size | Number of interventions | Description of interventions | Number of RCT | Outcome | Risk assessment tool |
| Fu et al. [15] | Acute gouty arthritis | 4931 | 10 | Western medicine, acupuncture + pricking blood and cupping, Chinese medicine + cupping, acupuncture and moxibustion, Chinese medicine, Western medicine + pricking blood and cupping, pricking blood and cupping, Western medicine + acupuncture, Western medicine + massage, and Western medicine + Chinese medicine | 66 | Effective rate | Jadad |
| Ding [16] | Abdominal distension after abdominal operation | 2047 | 7 | Acupoint application, acupoint injection, acupoint massage, moxibustion, TCM enema, TCM hot ironing, and routine nursing | 22 | Effective rate | Jadad |
| Li [17] | Poststroke depression | 1895 | 13 | Acupuncture + Chinese medicine, ear bean + Chinese medicine, electric acupuncture + Chinese medicine, moxibustion + Chinese medicine, auricular acupoint electroacupuncture + Chinese medicine, head acupuncture + acupoint embedding, auricular acupoint electroacupuncture + acupuncture, ear bean + acupuncture, acupuncture + acupoint injection, acupuncture + wuxing music, wuxing music + Chinese medicine, SSRIs, and acupuncture + moxibustion | 23 | Effective rate | Jadad |
| Bu et al. [18] | Optic atrophy | 1369 | 11 | Western medicine, acupuncture, acupuncture + moxibustion, ear point + Chinese medicine, electroacupuncture, acupuncture + Chinese and Western medicine, moxibustion + Chinese and Western medicine, electroacupuncture + Chinese and Western medicine, Chinese and Western medicine, Chinese medicine, and acupuncture + Western medicine | 16 | Effective rate, vision, horizon, and visual evoked potential | RoB |
| Zhang [19] | Ankylosing spondylitis | 2208 | 9 | Sulfasalazine, acupuncture, moxibustion, bee acupuncture, acupuncture + moxibustion, acupuncture + moxibustion + cupping, and moxibustion + bee needle | 25 | Effective rate | RoB |
| Song [20] | Polycystic ovary syndrome | 4605 | 14 | Acupuncture-medication therapy, Western medicine, acupuncture and moxibustion, acupuncture, acupuncture + ear points, moxibustion + Chinese medicine, acupuncture + ear points, acupuncture + placebo, placebo + Western medicine, Chinese medicine + Western medicine, placebo, acupoint thread-embedding therapy and medication, Chinese medicine, and moxibustion | 39 | Ovulation rate and pregnancy rate | RoB |
| Yang et al. [21] | Lumbar disc herniation | 2589 | 4 | Acupuncture, acupuncture + cupping, acupuncture + massage, and acupuncture + cupping + massage | 30 | Pain improvement, effectiveness, cure rate, recurrence rate, and economic indicators. | RoB |
| Li [22] | Primary dysmenorrhea | 4600 | 6 | Acupuncture, acupuncture + moxibustion, acupuncture + indirect moxibustion, warm acupuncture, electroacupuncture, and electroacupuncture + warm acupuncture | 56 | Effective rate, VAS, and dysmenorrhea symptom score | RoB |
| Jia et al. [23] | Chronic urticaria | 1186 | 9 | Acupoint catgut embedding, acupoint catgut embedding + loratadine, acupoint catgut embedding + mizolastine, acupoint catgut embedding + cetirizine, acupoint catgut embedding + epstein, loratadine, mizolastine, cetirizine, and epstein | 15 | Effective rate and adverse effect | RoB |
| Liu [24] | Knee osteoarthritis | 3417 | 6 | Hyaluronic acid (HA), needle knife, needle knife + HA, needle knife + internal medicine, needle knife + massage, and needle knife + acupuncture | 29 | Effective rate, VAS, and Lysholm function scores | Jadad |
| Feng [25] | Primary dysmenorrhea | 10259 | 9 | Multipoint + conventional Chinese medicine therapy, multipoint + Western medicine conventional therapy, single point + TCM, TCM, single point, multipoint, Western medicine routine therapy, and placebo | 103 | Effective rate, VAS, CMSS, and SF-MPQ | RoB |
| Liu [26] | Poststroke shoulder pain | 1898 | 9 | Rehabilitation, acupuncture, acupuncture + rehabilitation, acupuncture + massage, acupuncture + TCM fumigation + rehabilitation, acupuncture + massage + cupping, acupuncture + massage + rehabilitation, acupuncture + TCM + rehabilitation, and acupuncture + joint loosening + rehabilitation | 25 | Effective rate, FMA, and MBI | RoB |
| Yang et al. [27] | Premature ovarian insufficiency | 3046 | 18 | HRT, acupuncture, moxibustion, needle-warming moxibustion, electroacupuncture, catgut implantation at acupoint , TCM, acupuncture + TCM, moxibustion + TCM, electroacupuncture + TCM, acupoint application + TCM, auricular point sticking + TCM, acupressure + TCM, catgut implantation at acupoint + TCM, acupuncture + HRT, electroacupuncture + HRT, catgut implantation at acupoint + HRT, and acupuncture + TCM + HRT | 43 | Effective rate and adverse effect | RoB |
| Zhu et al. [28] | Chronic constipation | 11032 | 10 | Acupuncture, polyethylene glycol, lactulose, linaclotide, lubiprostone, bisacodyl, prucalopride, sham acupuncture, tegaserod, and placebo | 40 | Symptoms of chronic constipation and side effects | Jadad |
| Zheng [29] | Chronic functional constipation | 4324 | 8 | Acupuncture, mosapride, insoluble fiber, massage, mineral water, probiotic, TENS, and moxibustion | 33 | Weekly stool frequency, Bristol score, responder rate, and adverse event | RoB |
| Qin [30] | Chronic prostatitis/chronic pelvic pain syndrome | 1203 | 7 | Acupuncture, electroacupuncture, alpha-blockers, antibiotics, dual therapy, sham acupuncture, and placebo | 12 | NIH-CPSI QoL score | RoB |
| Li et al. [31] | Knee osteoarthritis | 2065 | 7 | Common manual acupuncture, electroacupuncture, fire needle, warm needle, placebo, sham needle, and education | 16 | WOMAC, stiffness, and physical function scores | RoB |
| Mo et al. [32] | Lumbar disc herniation | 13075 | 4 | Tuina, traction, acupuncture, and Chinese herbs | 121 | Invalid rate, cure rate, VAS, and JOA | RoB |
| Luo et al. [33] | Primary dysmenorrhea | 1511 | 8 | Traditional acupuncture, eye acupuncture, wrist-ankle acupuncture, superficial acupuncture, moxibustion, electroacupuncture, ear acupuncture, and abdominal acupuncture | 17 | Effective rate | RoB |
| Yeh et al. [34] | Psoriasis | 869 | 6 | Acupuncture, acupressure, acupoint bloodletting, acupoint catgut embedding, Chinese herbal medicine, and narrow-band ultraviolet B | 10 | PASI and TCM | Jadad RoB |
| Chen et al. [35] | Migraine | 3656 | 9 | Acupuncture, flunarizine, metoprolol, propranolol, propranolol + flunarizine, sham acupuncture, topiramate, usual care, and waiting list | 19 | Migraine episodes, the number of migraine days, migraine frequency, responder rate, and adverse event rate | RoB |
| Tan et al. [36] | Essential hypertension | 2649 | 15 | Electroacupuncture, moxibustion, warm needle therapy, sham acupuncture, behavioral therapy, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), calcium channel blocker (CCB), beta-blocker, acupuncture-combined ACEI, acupuncture-combined CCB, acupuncture-combined behavior, electroacupuncture-combined CCB, sham acupuncture, and nontreatment | 31 | posttreatment BP changes, response rate, and MACE | RoB |
| Li et al. [37] | Myofascial pain syndrome | 1692 | 22 | Placebo-sham, MA, EA, DN, MET, TCT, MT, LTrP-I, MDIMST, MSN, TTM, BTX-A-TrP-I, FN, SWAM, EA&ESNC, SPM, DN&MET, BTrP-I, TrP-DN&EDU, Stretch, DN&Stretch, laser, and PT | 33 | Pain measurement (VAS, NRS, and PPT), adverse events (ROM), and functional status | RoB |
| Zhu et al. [38] | Diarrhea-predominant irritable bowel syndrome | 9369 | 7 | Acupuncture, sham acupuncture, pinaverium bromide, alosetron, eluxadoline, ramosetron, and rifaximin | 29 | Effective rate, side effects (constipation and rash), and common acupuncture points. | Jadad |
| Xiong and Chen [39] | Diabetic peripheral neuropathy | 2602 | 7 | Manual acupuncture, electroacupuncture, needle knocking acupuncture, warm needling and moxibustion, mecobalamin, no interventions, and vitamin B | 40 | global symptom improvement | non |
| Yang et al. [40] | Heart failure | 2116 | 5 | Acupuncture, moxibustion, acupoint application, acupoint injection, and warming acupuncture-moxibustion | 26 | HFC and LVEF | RoB |
| Zhang et al. [41] | Obesity | 2283 | 6 | AAS, EA, ACE, WA, AR: acupuncture and related therapies and combination of acupuncture and related therapies. | 34 | BW, BMI, and adverse events | RoB |
| Corbett 2013 [42] | Knee osteoarthritis | 9709 | 8 | Interferential therapy, acupuncture, TENS, pulsed electrical stimulation, balneotherapy, aerobic exercise, sham acupuncture, and muscle-strengthening exercise | 114 | WOMAC pain | RoB |
| Wang et al. [43] | Chronic fatigue syndrome | 2255 | 5 | CbAM, SAM, Chinese herbal medicine, Western medicine, and sham acupuncture | 31 | Effective rate | RoB |
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