Research Article
Phytochemical Analysis and Investigation of the Antimicrobial and Cytotoxic Activities of Croton dichogamus Pax Crude Root Extracts
Table 4
The toxicity profile of the acetonic, aqueous, and hydroethanolic root extracts of C. dichogamus as compared to vincristine sulphate.
| | Sample | Average mortality per test dose | Lethal concentration | Toxicity | | 10 μg/mL | 100 μg/mL | 1000 μg/mL | LC50 (95% confidence interval) | Meyer’s criteria |
| | Vincristine sulphate | 3 | 31 | 50 | 65.04 (46.07–92.17) | Highly cytotoxic | | Acetone extract of C. dichogamus | 33 | 43 | 50 | 4.148 (0.58–9.87) | Highly cytotoxic | | Aqueous extract of C. dichogamus | 8 | 35 | 50 | 42.61 (28.86–62.26) | Highly cytotoxic | | Hydroethanolic extract of C. dichogamus | 0 | 35 | 50 | 76.09 (58.69–133.33) | Highly cytotoxic |
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