Highly Expressed CYBRD1 Associated with Glioma Recurrence Regulates the Immune Response of Glioma Cells to Interferon

Figure 1

CYBRD1 expression in tissue samples according to an online database. (a) CYBRD1 expression in 25 primary glioma tissues and 18 recurrent glioma tissues, according to GSE62153. (b) CYBRD1 expression in 70 primary glioma tissues and 10 recurrent glioma tissues, according to GSE7696. (c) CYBRD1 expression in 77 primary glioma tissues and 23 recurrent glioma tissues, according to GSE4271. (d) CYBRD1 expression in 154 primary glioma tissues and 13 recurrent glioma tissues, according to TCGA-GBM. (e) CYBRD1 expression in 422 primary glioma tissues and 271 recurrent glioma tissues, according to CGGA-RNAseq-693. (f) CYBRD1 expression in 256 primary glioma tissues and 14 recurrent glioma tissues, according to IVY-RNAseq. (g) CYBRD1 expression in 530 WHO II/III glioma cases and 172 WHO IV glioma cases, according to TCGA-GBMLGG. (h) CYBRD1 expression in 188 WHO II glioma cases, 255 WHO III glioma cases, and 249 WHO IV glioma cases, according to CGGA-RNAseq-693. (i) Cases from TCGA-GBMLGG were grouped by the median value of CYBRD1 expression into the high and low CYBRD1 groups. The correlation of CYBRD1 expression and the overall survival in patients with glioma was analyzed using a Cox proportional hazards model and Log Rank test, and the results were shown as Kaplan–Meier curves. (j) Cases from CGGA-RNAseq were grouped by the median value of CYBRD1 expression into the high and low CYBRD1 groups. The correlation of CYBRD1 expression and the overall survival in patients with glioma was analyzed using a Cox proportional hazards model and Log Rank test, and the results were shown as Kaplan–Meier curves.

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