Curcumin Synergistically Enhances the Cytotoxicity of Arsenic Trioxide in U266 Cells by Increasing Arsenic Uptake

Figure 3

Analysis of U266 cells treated with ATO, curcumin, and their combination. (a) The inhibition rates. (b) The analysis of the curcumin and ATO combined application index. (c, d) The apoptotic rates. indicates for the combination group compared with the ATO alone groups; indicates ; indicates for the combination group compared with curcumin alone; and indicates . Group a: ATO 2.5 μmol/L, curcumin 10 μmol/L; group b: ATO 5 μmol/L, curcumin 20 μmol/L. (e) The intracellular arsenic content. indicates for the combination group compared with ATO treatment alone.

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