Research Article

Acute Toxicity, Phytochemical Screening, Analgesic, and Anti-Inflammatory Activities of Aqueous and Methanol Root Extracts of Maerua triphylla A. Rich. (Capparaceae)

Table 2

Effect of M. triphylla root aqueous and methanol extract on acetic acid-induced writhing in Swiss albino mice.

Dose (mg/kg bw)Aqueous root extractMethanol root extract
Mean number of writhes% writhing inhibitionMean number of writhes% writhing inhibition

2013.0085.31 ± 1.13a15.8081.84 ± 1.51a
1005.8093.43 ± 1.26b10.0088.43 ± 1.25bc
5003.6095.97 ± 1.16b6.2092.55 ± 1.20c
ASA (75 mg/kg bw)16.6081.08 ± 1.16a15.6082.17 ± 2.11ab
Physiological saline88.20088.000

Values are presented as mean ± SEM. Means with different superscript letters along the same column are significantly different (one-way ANOVA and Tukey’s test; ). ASA: acetylsalicylic acid.