Research Article

Improvement of Bronchial Immune Hypersensitivity Reaction Using Extracts from Chrysanthemum morifolium Ramatuelle and Scutellaria baicalensis Georgi

Table 1

Effect of different mixing ratios of chrysanthemum and skullcap on immune factors.

FactorGroupa,b
6 : 47 : 38 : 2
501002005010020050100200

White bloodBALF↓↓↓↓↓↓↓↓
Eosinophil↓↓↓↓↓↓↓↓↓↓↓↓
IL-1βSerum↓↓↓↓↓↓
BALF↓↓↓↓↓↓

IL-4Serum↓↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓↓

IL-5Serum↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓

IL-6Serum↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓

IL-10Serum↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓

IL-13Serum↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓

IL-17ASerum↓↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓

IL-17FSerum↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓↓

IL-17ESerum↓↓↓↓↓↓↓↓↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓

IL-2Serum↑↑
BALF↑↑

IFN-γSerum↑↑↑↑↑↑↑↑↑↑↑
BALF↑↑↑↑↑↑↑↑↑↑↑

IgESerum↓↓↓↓
BALF↓↓↓↓↓↓↓↓↓↓↓↓↓↓

HistamineSerum↓↓↓↓
BALF

TSLPSerum↓↓↓↓↓↓
BALF↓↓↓↓↓↓

BALF: bronchoalveolar lavage fluid; IL: interleukin; TSLP: thymic stromal lymphopoietin. aThe chrysanthemum and skullcap extracts were mixed in a 6 : 4, 7 : 3, or 8 : 2 ratio (row 2). bThe mice were orally administered 50, 100, or 200 mg/kg BW of the mixture (row 3).