Combined Metabolomics and Network Toxicology to Explore the Molecular Mechanism of <i>Phytolacca acinose</i> Roxb-Induced Hepatotoxicity in Zebrafish Larvae in Vivo

<div>(a) Visualization of the overall metabolite profile difference between the PAR-treated group and the control group including the OPLS-DA predictive/discriminate score plot (a<sub>1</sub>), 1000 permutation tests (a<sub>2</sub>), and V-plot (a<sub>3</sub>); (b) differential metabolic pathways between the PAR-treated group and the control group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4: Combined Metabolomics and Network Toxicology to Explore the Molecular Mechanism of <i>Phytolacca acinose</i> Roxb-Induced Hepatotoxicity in Zebrafish Larvae in Vivo 

Figure 4 | Combined Metabolomics and Network Toxicology to Explore the Molecular Mechanism of Phytolacca acinose Roxb-Induced Hepatotoxicity in Zebrafish Larvae in Vivo 