Antifungal Activity and Acute and Repeated-Dose Toxicity Study of Geranyl Cinnamate Ester in Mice

Figure 3

Effect of geranyl cinnamate ester (GCE) acute treatment (2000 mg/kg, p.o.) on relative body weight (%) of female mice (n = 3–6 mice/group) (a) and food intake (g food intake/g mice/day) (b). Data are expressed as mean + SEM. Two-way repeated-measures ANOVA post hoc Bonferroni. Relative body weight (a): different from the initial weight (day 0). (corn oil-treated, 10 mL/kg, p.o.), ^## (GCE-treated, 2000 mg/kg, p.o.), and ^### (GCE-treated, 2000 mg/kg, p.o.), and different from the vehicle group (corn oil-treated, 10 mL/kg, p.o.) in the same day of measurement. Food intake (b): different from the vehicle group (corn oil-treated, 10 mL/kg, p.o.).

(a)

(b)