Antifungal Activity and Acute and Repeated-Dose Toxicity Study of Geranyl Cinnamate Ester in Mice

Figure 8

Effect of the geranyl cinnamate ester (GCE) repeated-dose treatment (1, 2, and 4 mg/kg, p.o.) on male mice biochemical parameters. Data are expressed as mean + SEM. One-way ANOVA post hoc Bonferroni (n = 3–5 animals/group). different from vehicle group; ^# different from GCE 1 mg/kg-treated group; ^§ different from GCE 2 mg/kg-treated group; ^@ different from GCE 4 mg/kg-treated group. (a) Serum sodium (Na); (b) potassium (K); (c) total protein; (d) albumin; (e) glucose; (f) total cholesterol; (g) cholesterol fraction (LDL); (h) triglycerides; (i) alanine aminotransferase (ALT); (j) alkaline phosphatase (AP); (k) creatinine and (l) uric acid were evaluated.

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