Simultaneous Determination of Ten Bioactive Components from Shenling Baizhu San in Rat Plasma by UHPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Two Models of Ulcerative Colitis Rats

Table 2

Linearity of each component (n = 5).

Analyte	Calibration curves	Correlation coefficient (r)	Linear range (ng·mL^−1)	LLOQ (ng·mL^−1)
PAN	Y = 0.00102X + 6.1385e − 4	0.9990	0.44∼397.50	0.44
Rg1	Y = 2.525e − 5X + 9.435e − 5	0.9990	0.63∼388.50	0.63
ATA-I	Y = 0.00290X − 0.00119	0.9990	0.44∼400.50	0.44
ATA-III	Y = 0.00439X + 0.22385	0.9990	0.54∼490.50	0.54
PA	Y = 7.6916e − 5X + 0.00537	0.9995	0.38∼355.50	0.38
NEF	Y = 0.00133X + 0.00776	0.9994	0.31∼279.00	0.31
NUC	Y = 0.02406X − 0.00469	0.9991	0.41∼367.50	0.41
DG	Y = 2.563e − 4X + 0.00142	0.9994	0.50∼447.00	0.50
PD	Y = 3.5807e − 5X + 2.740e − 5	0.9990	0.42∼382.50	0.42
ISL	Y = 0.00220X − 2.625e − 4	0.9992	0.39∼356.10	0.39