Simultaneous Determination of Ten Bioactive Components from Shenling Baizhu San in Rat Plasma by UHPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Two Models of Ulcerative Colitis Rats

Table 4

Stability of the components in rat plasma under a variety of storage and process conditions (n = 5).

Analyte	Concentration (ng·mL^−1)	RSD%
		Short-term stability (room temperature, 4 h)	Autosampler stability (4°C, 12 h)	Freeze-thaw cycles (three freeze-thaw cycles)	Long-term stability (−20°C, 30 d)
PAN	0.80	6.85	4.54	10.71	12.81
	99.38	6.24	7.61	10.77	8.94
	397.50	6.76	3.57	11.82	6.43
Rg1	1.14	3.38	3.38	14.47	10.79
	142.13	3.41	3.41	9.60	7.60
	568.50	10.88	8.21	7.19	8.95
ATA-I	0.80	8.86	8.86	11.17	6.05
	100.13	11.79	11.79	6.24	8.53
	400.50	8.59	8.59	9.48	6.56
ATA-III	0.98	10.49	10.49	11.56	2.56
	122.63	7.59	7.59	9.19	7.01
	490.50	3.12	3.12	9.35	9.19
PA	0.69	6.81	7.55	10.06	10.06
	62.25	6.34	3.92	13.50	13.50
	345.00	8.88	2.26	5.01	5.01
NEF	0.31	3.85	6.63	2.95	7.93
	69.75	5.27	7.61	9.26	13.41
	279.00	2.16	5.15	7.86	14.69
NUC	0.74	4.11	14.46	12.64	13.16
	69.75	3.41	8.23	12.59	11.06
	225.00	4.01	6.36	6.27	11.19
DG	0.89	12.11	4.39	3.99	8.52
	111.75	9.85	3.12	13.42	10.94
	447.00	7.59	1.82	9.86	9.65
PD	0.77	11.69	6.16	11.97	15.38
	95.63	5.01	2.99	5.27	11.74
	382.50	3.27	5.84	7.83	10.07
ISL	0.71	5.72	7.13	5.72	11.80
	88.86	1.35	1.54	1.35	13.57
	355.50	2.21	6.22	2.21	12.65