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| Author (year) | Country | Sample sizes (M/F) | Mean age (I/C) | Diagnosis | Cancer stage | Diagnostic criteria of insomnia | Criteria of auricular acupoints | Anticancer treatment | Intervention material | Control | Acupoint selection | Course of treatment | Outcome measures | Adverse effects | Drop-out (I/C) | Follow-up |
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| Lei (2019) | China | 96 (60/36) | 51.49 ± 8.40/52.49 ± 7.09 | Primary liver cancer | I–III | PSQI > 7 | GB/T13734-2008 | Surgery or other therapies | Vaccaria seeds | Routine care | Shenmen, subcortex, heart, sympathetic nerve, endocrine, liver, and spleen | 3–5 min/time, 3 times/d, 28 d | PSQI and SRSS | None | I2/C0 | Not reported |
| Lu (2017) | China | 60 (42/18) | Not reported | Lung cancer | Not reported | Not reported | Not reported | Radiotherapy | Vaccaria seeds | Routine care | Heart, Shenmen, anterior lobe, occiput, and subcortex | 10 press/time, 5-6 times/d, 30 d | AIS | None | None | Not reported |
| Kuo (2018) | China | 47 | 51.5 ± 13.23/54.7 ± 14.56 | Ovarian cancer | I–IV | PSQI > 5 | Not reported | Chemotherapy | Vaccaria seeds | Routine care | Shenmen, heart, subcortex, and endocrine | 3 min/time, 3 times/d, 6 w | PSQI | None | I3/C4 | Not reported |
| Yoon (2019) | Korea | 46 | 45.05 ± 8.33/44.57 ± 8.34 | Breast cancer | I–III | ISI 8 | Not reported | Chemotherapy | Vaccaria seeds | Placebo auricular pressure (helix control points) | Shenmen, heart, anterior lobe, and occiput | 1 min/time, once/d, 6 d/w, 6 w | PSQI, IL-6, TNF-α, cortisol, C-reactive protein, and fit bit tracker device | None | I3/C2 | Not reported |
| Lin (2018) | China | 60 | 36.41 ± 9.13/37.27 ± 10.21 | Breast cancer | II | The Chinese Classification and the Diagnose Criterion of Mental Disorder | Not reported | Chemotherapy | Vaccaria seeds | Routine care | Shenmen, heart, kidney, subcortex, and sympathetic nerve | 3–5 min/time, 3–5 times/d, 11 d | PSQI | None | None | Not reported |
| Hughes (2015) | Britain | 6 (2/4) | 52.25 ± 12.31/54.00 ± 2.83 | Breast cancer 4 and colorectal cancer 2 | Not reported | PSQI 5 | Acupuncture/acupressure textbooks; consult an acupuncturist | Chemotherapy or radiotherapy | Vaccaria seeds | No treatment | Bilateral Shenmen, any two from insomnia 1, insomnia 2, heart, liver, kidney, and subcortex | 1 min/time, once/d, 35 d | PSQI | Slight, transient pain of the ear | None | Not reported |
| Wei (2019) | China | 148 (80/68) | 59.28 ± 9.41/59.14 ± 9.23 | Lung cancer 30, intestinal cancer 18, gastric cancer 8, breast cancer 8, and pancreatic cancer 10 | Not reported | Guidelines for diagnosis and treatment of insomnia in Chinese adults | Not reported | Not reported | Vaccaria seeds | Routine care | Shenmen, heart, endocrine, and spleen | 1-2 min/time, 6 times/d, 14 d | PSQI | None | None | Not reported |
| Song (2014) | China | 100 | Not reported | Gastric cancer 40, lung cancer 40, liver cancer 12, and gallbladder cancer 8 | Not reported | PSQI | Not reported | Chemotherapy | Vaccaria seeds | Routine care | Subcortex, heart, sympathetic nerve, Shenmen, sympathetic nerve, ear apex, and brain stem, combined with liver, gallbladder, lung, and stomach | 2-3 min/time, 10 d | PSQI | None | None | Not reported |
| Fan (2015) | China | 125 | 60.0 ± 14.4/63.2 ± 13.5 | Not reported | Not reported | CAIS-8 8 | Not reported | Chemotherapy, CCRT, or other therapies | Magnetic beads | Routine care | Shenmen, heart, occiput, and subcortex | 20–30 press /time, 3 times/d, 28 d | AIS | None | I26/C10 | Not reported |
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