Research Article
Effect of Sijunzi Pills on Pharmacokinetics of Omeprazole in Beagle Dogs by HPLC-UV: A Herb-Drug Interaction Study
Table 1
The precision and accuracy of omeprazole in beagle dog plasma (n = 6, mean ± SD).
| | Added (ng/mL) | Intraday | Interday | | Found (ng/mL) | RSD (%) | RE (%) | Found (ng/mL) | RSD (%) | RE (%) |
| | 5 | 5.08 ± 0.36 | 6.99 | 1.63 | 4.96 ± 0.37 | 7.46 | −0.83 | | 10 | 9.92 ± 0.69 | 6.95 | −0.82 | 10.12 ± 0.55 | 5.44 | 1.18 | | 250 | 248.45 ± 13.44 | 5.41 | −0.62 | 252.49 ± 11.51 | 4.56 | 1.00 | | 750 | 758.32 ± 19.83 | 2.61 | 1.11 | 748.60 ± 19.85 | 2.65 | −0.19 |
|
|
