Efficacy and Safety of Dahuang Zhechong Pill in Silicosis: A Randomized Controlled Trial
Table 1
Baseline characteristics of the study participants.
CG, n = 29
DG, n = 29
value
Mean (SD) or n (%)
CI
Mean (SD) or n (%)
CI
General information
Male
29 (100%)
—
29 (100%)
—
—
Female
0 (0%)
—
0 (0%)
—
—
Age, year
69.3 (8.0)
66.3 to 72.4
71.8 (9.0)
68.4 to 75.2
0.279
Height, cm
165.7 (4.1)
164.1 to 167.3
163.8 (5.1)
161.9 to 165.8
0.129
Weight, kg
63.5 (8.9)
60.1 to 66.9
61.9 ± (5.9)
59.7 to 64.2
0.427
BMI, kg/m2
23.1 (3.1)
21.9 to 24.3
23.1 (1.9)
22.4 to 23.8
0.933
Complications and previous history
Smoke history
24 (82.8%)
—
25 (86.2%)
—
0.717
Emphysema
12 (41.4%)
—
15 (51.7%)
—
0.430
Respiratory failure
3 (10.3%)
—
3 (10.3%)
—
1.000
Tuberculosis
3 (10.3%)
—
5 (17.2%)
—
0.446
Pneumothorax
2 (6.9%)
—
4 (13.8%)
—
0.389
Bullae
3 (10.3%)
—
5 (17.2%)
—
0.446
Pulmonary function
FVC % pred
66.0 (16.1)
59.8 to 72.2
62.7 (15.9)
56.4 to 69.0
0.451
DLCO % pred
63.4 (19.1)
56.0 to 70.8
62.2 (16.2)
55.8 to 68.6
0.803
Hypoxia and exercise capacity
SpO2
88.4 (1.7)
87.8 to 89.1
88.1 (1.7)
87.5 to 88.7
0.481
6WMD
306.7 (98.6)
269.2 to344.2
306.2 (103.9)
266.7 to 345.7
0.985
K-BILD
Total
56.6 (9.8)
52.8 to 60.3
56.8 (9.3)
53.2 to 60.28
0.935
Breathlessness and activities
41.1 (15.4)
35.2 to 46.9
40.3 (13.2)
35.2 to 45.3
0.823
Chest symptoms
51.3 (15.5)
45.5 to 57.2
50.6 (11.8)
46.1 to 55.1
0.833
Psychological symptoms
64.0 (6.4)
61.6 to 66.5
65.2 (7.9)
62.2 to 68.2
0.551
SD = standard deviations; n = number; CI = confidence interval; the sample size of FVC% and DLCO% in DHZCP group was 27 and in No DHZCP group was 28; statistical difference of smoke history was determined by the Pearson chi-square test, and other indexes were determined by the independent-samples t-test.
