Study of the Antimalarial Activity of the Leaf Extracts and Fractions of Persea americana and Dacryodes edulis and Their HPLC Analysis

Table 1

Results of the acute toxicity studies of the extracts of P. americana and D. edulis.

Experiment	Number of animals	Extract
		Dose (mg/kg)	PA	DE
			Mortality rate
Phase I	3	10	0/3	0/3
	3	100	0/3	0/3
	3	1000	0/3	0/3
Phase II	1	1600	0/1	0/1
	1	2900	0/1	0/1
	1	3600	0/1	0/1
	1	5000	0/1	1/1
LD50(mg/kg)			>5000	4243