Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways

Figure 2

Effects of AU on the LTA-induced expression COX-2, IL-1β, and TNF-α in RAW 264.7 macrophages. (a)–(d) Cells were untreated or pretreated with AU (5 and 10 μM) for 30 min and then stimulated with LTA (5 μg/ml) for 24 h. COX-2, IL-1β, and TNF-α were detected as described in Section 2. The values shown are the means ± S.E.M. of four independent experiments. and vs. the control cells; , , and vs. LTA-stimulated cells.

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