Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway

<div>Presentation of mechanism for the neuroprotective role of HPTQ in DCD mice model. HPTQ could reduce the release of insulin, activate CREB/BDNF/TrkB signaling pathway, and inhibit mitochondria-related apoptosis signals Bax/Bcl-2 and caspase-3 pathway in the brain hippocampus.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 11

Figure 11: Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway 

Figure 11 | Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway 