Research Article
Unveiling the Mechanism of Principal Drugs of Lianpu Drink on Chronic Gastritis by Network Pharmacology
Table 2
The information of target proteins of “MOR” predicted by network pharmacology analyses.
| Uniprot no. | Protein name | Gene name | Closeness centrality | Degree | Betweenness centrality |
| P41182 | B-cell lymphoma 6 protein | BCL6 | 0.2056 | 8 | 0.0369 | P17535 | Transcription factor jun-D | JUND | 0.1857 | 4 | 0.0023 | P15941 | Mucin-1 | MUC1 | 0.2361 | 3 | 0.0339 | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | IKBKE | 0.1967 | 5 | 0.0052 | Q16539 | Mitogen-activated protein kinase 14 | MAPK14 | 0.2029 | 5 | 0.0022 | Q03164 | Histone-lysine N-methyltransferase 2A | KMT2A | 0.1989 | 5 | 0.0056 | P35968 | Vascular endothelial growth factor receptor 2 | KDR | 0.1856 | 11 | 0.0189 | Q99558 | Mitogen-activated protein kinase kinasekinase 14 | MAP3K14 | 0.1887 | 13 | 0.0111 | P19838 | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | 0.1959 | 21 | 0.0189 | P04637 | Cellular tumor antigen p53 | TP53 | 0.2289 | 60 | 0.1438 | O15350 | Tumor protein p73 | TP73 | 0.1879 | 9 | 0.0037 | P09874 | Poly [ADP-ribose] polymerase 1 | PARP1 | 0.2023 | 11 | 0.0449 | P60900 | Proteasome subunit alpha type-6 | PSMA6 | 0.1846 | 3 | 0.0022 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | RIPK1 | 0.1833 | 7 | 0.0475 | Q86WV6 | Stimulator of interferon genes protein | STING1 | 0.1851 | 8 | 0.0049 | Q04206 | Transcription factor p65 | RELA | 0.1974 | 19 | 0.0133 | P24385 | G1/S-specific cyclin-D1 | CCND1 | 0.2329 | 10 | 0.0877 | P05412 | Transcription factor AP-1 | JUN | 0.2135 | 13 | 0.0278 | P25963 | NF-kappa-B inhibitor alpha | NFKBIA | 0.2177 | 18 | 0.0477 | P06396 | Gelsolin | GSN | 0.2326 | 5 | 0.0276 | P31749 | RAC-alpha serine/threonine-protein kinase | AKT1 | 0.2153 | 13 | 0.0323 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | NLRP1 | 0.1853 | 4 | 0.0141 | Q16665 | Hypoxia-inducible factor 1-alpha | HIF1A | 0.2139 | 12 | 0.0151 | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | CHUK | 0.2166 | 18 | 0.0318 | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB | 0.2158 | 15 | 0.0206 | Q9Y6K9 | NF-kappa-B essential modulator | IKBKG | 0.2163 | 23 | 0.0446 |
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