Composition of the Essential Oil Thymus schimperi and Evaluation of Its Acute and Subacute Toxicity in Wistar Albino Rats: In Silico Toxicity Studies
Table 5
Body and organ weights of rats in the control and T. schimperi essential oil-treated groups in the subacute toxicity study.
Parameters
Control
Treatment of T. schimperi essential oil
65 mg/kg
130 mg/kg
260 mg/kg
Day 0
201.00 ± 2.78
198.00 ± 2.22
199.00 ± 1.98
198.00 ± 2.02
Day 7
207.00 ± 4.23
206.00 ± 2.50
207.00 ± 2.90
202.50 ± 2.42
Day 14
210.50 ± 4.41
210.00 ± 2.61
210.50 ± 3.56
205.50 ± 2.81
Day 21
212.50 ± 4.86
211.00 ± 3.67
212.00 ± 3.62
211.50 ± 4.56
Day 28
215.50 ± 4.89
215.00 ± 3.45
213.00 ± 4.71
213.50 ± 3.65
Organs’ weight (g)
Liver
5.58 ± 0.68
6.91 ± 0.20
6.47 ± 0.49
5.48 ± 0.65
Kidney
1.47 ± 0.15
1.20 ± 0.10
1.56 ± 0.06
1.40 ± 0.12
Heart
0.85 ± 0.06
0.68 ± 0.09
0.88 ± 0.02
0.72 ± 0.04
Spleen
0.56 ± 0.08
0.47 ± 0.09
0.46 ± 0.10
0.64 ± 0.07
Pancreas
1.14 ± 0.31
1.00 ± 0.20
1.01 ± 0.15
1.00 ± 0.33
The dataareexpressed as mean ± SEM,n = 10 for each group. There was no statistical differencebetweenthe control and theT.schimperiessential oil treatment groups ().