Research Article

Composition of the Essential Oil Thymus schimperi and Evaluation of Its Acute and Subacute Toxicity in Wistar Albino Rats: In Silico Toxicity Studies

Table 5

Body and organ weights of rats in the control and T. schimperi essential oil-treated groups in the subacute toxicity study.

ParametersControlTreatment of T. schimperi essential oil
65 mg/kg130 mg/kg260 mg/kg

Day 0201.00 ± 2.78198.00 ± 2.22199.00 ± 1.98198.00 ± 2.02
Day 7207.00 ± 4.23206.00 ± 2.50207.00 ± 2.90202.50 ± 2.42
Day 14210.50 ± 4.41210.00 ± 2.61210.50 ± 3.56205.50 ± 2.81
Day 21212.50 ± 4.86211.00 ± 3.67212.00 ± 3.62211.50 ± 4.56
Day 28215.50 ± 4.89215.00 ± 3.45213.00 ± 4.71213.50 ± 3.65

Organs’ weight (g)
Liver5.58 ± 0.686.91 ± 0.206.47 ± 0.495.48 ± 0.65
Kidney1.47 ± 0.151.20 ± 0.101.56 ± 0.061.40 ± 0.12
Heart0.85 ± 0.060.68 ± 0.090.88 ± 0.020.72 ± 0.04
Spleen0.56 ± 0.080.47 ± 0.090.46 ± 0.100.64 ± 0.07
Pancreas1.14 ± 0.311.00 ± 0.201.01 ± 0.151.00 ± 0.33

The dataareexpressed as mean ± SEM,n = 10 for each group. There was no statistical differencebetweenthe control and theT.schimperiessential oil treatment groups ().