Composition of the Essential Oil Thymus schimperi and Evaluation of Its Acute and Subacute Toxicity in Wistar Albino Rats: In Silico Toxicity Studies

Table 6

Hematological values of rats in the control and T. schimperi essential oil-treated groups in the subacute toxicity study.

Parameter	Control	Treatment of T. schimperi essential oil
		65 mg/kg	130 mg/kg	260 mg/kg
RBC (×10^6/μL)	8.50 ± 0.15	7.96 ± 0.20	8.04 ± 0.19	7.25 ± 1.22
WBC (×10^3/μL)	14.09 ± 1.37	12.94 ± 1.04	11.80 ± 1.50	7.40 ± 1.79^a
Hb (g/dl)	16.70 ± 0.31	15.82 ± 0.30	16.28 ± 0.39	14.48 ± 2.29
HCT (%)	47.73 ± 0.84	47.98 ± 0.69	48.37 ± 1.36	41.97 ± 7.03
MCV (pg)	56.13 ± 0.49	57.57 ± 1.70	58.93 ± 0.80	60.15 ± 0.39^a
MCH (pg)	19.63 ± 0.16	19.87 ± 0.17	20.25 ± 0.19	20.80 ± 0.97
MCHC (g/dl)	34.98 ± 0.54	32.97 ± 0.67	33.70 ± 0.33	35.68 ± 1.46
PLT ((×10^3/μL)	942.00 ± 120.50	952.00 ± 162.87	830.00 ± 79.07	804.50 ± 156.68

The data are expressed as mean ± SEM, n = 10 for each group. ^aSignificant difference compared to the control group (). RBC: red blood cells; WBC: white blood cells; Hb: hemoglobin; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; PLT: platelets.