Kochia scoparia Saponin Momordin Ic Modulates HaCaT Cell Proliferation and Apoptosis via the Wnt/β-Catenin Pathway

Figure 3

Momordin Ic treatment inhibits the Wnt/β-catenin signaling in HaCaT cells. Target cells were treated with 25 μmol/L Momordin Ic for 48 h and examined for the mRNA expression of β-catenin, c-myc, and VEGF by qRT-PCR (a); the protein levels of β-catenin, c-myc, and VEGF by immunoblotting (b); the content and distribution of β-catenin by immunofluorescent (IF) staining (c) (scale bar is 20 μm). .

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