Network Pharmacology-Based Analysis of the Underlying Mechanism of Huajiao for Pain Relief

<div>Molecular docking between the 5 amide alkaloids and p38<i>α</i>. (a) 3D mimic diagram of (6RS)-(2E,7E,9E)-6-hydroxy-N-(2-hydroxy-2-methylpropyl)-11-oxo-2,7,9-dodecatrienamide docking with p38<i>α</i>. (b) Partially enlarged view of 3D mimic diagram. (c) 2D mimic diagram of (6RS)-(2E,7E,9E)-6-hydroxy-N-(2-hydroxy-2-methylpropyl)-11-oxo-2,7,9-dodecatrienamide docking with p38<i>α</i>. (d) 3D mimic diagram of 5 amide alkaloids docking with p38<i>α</i>.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Network Pharmacology-Based Analysis of the Underlying Mechanism of Huajiao for Pain Relief 