Study on Mechanism of Jiawei Chaiqin Wendan Decoction in Treatment of Vestibular Migraine Based on Network Pharmacology and Molecular Docking Technology

Table 3

The binding free energy of 10 small molecules with top 5 genes.

Molecule name	Affinity (kcal/mol)
	IL6	PTGS2	MAPK1	MAPK3	CGRP
Beta-sitosterol	−5.9	−9.2	−7.5	−8.7	−6.7
Dihydrotanshinlactone	−7.8	−9.5	−8.9	−10.8	−8.2
Kaempferol	−7.6	−9.2	−7.7	−9.3	−9.0
Luteolin	−7.5	−10.0	−8.1	−9.4	−8.8
Naringenin	−7.2	−9.3	−8.0	−9.3	−8.5
Nobiletin	−6.2	−8.7	−6.9	−8.5	−7.9
Quercetin	−7.7	−9.6	−7.5	−9.3	−9.2
Salviolone	−7.2	−8.6	−9.1	−10.6	−7.7
Tanshinone iia	−7.6	−9.9	−8.6	−11.5	−7.9
Wogonin	−7.1	−9.4	−7.7	−9.3	−7.4