Huoxue Jiedu Huayu Formula Alleviates Cell Pyroptosis in Contralateral Kidneys of 6-Month-Old UUO Rats through the NLRP3/Caspase-1/IL-1<i>β</i> Pathway

<div>The treatment with Huoxue Jiedu Huayu formula and spironolactone, respectively, depressed DNA damage in the contralateral kidneys of 6-month-old UUO rats, which was an important feature of pyroptosis. (a) DNA damage was evaluated by TUNEL. The brown nuclei were the sites of positive expression. 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Huoxue Jiedu Huayu Formula Alleviates Cell Pyroptosis in Contralateral Kidneys of 6-Month-Old UUO Rats through the NLRP3/Caspase-1/IL-1<i>β</i> Pathway 

Figure 5 | Huoxue Jiedu Huayu Formula Alleviates Cell Pyroptosis in Contralateral Kidneys of 6-Month-Old UUO Rats through the NLRP3/Caspase-1/IL-1β Pathway 