Mechanism by Which Tong Xie Yao Fang Heals the Intestinal Mucosa of Rats with Ulcerative Colitis through the Hippo Pathway

Figure 1

TXYF significantly alleviated UC induced by TNBS. (a) Body weight of every rat was measured per day (n = 12 in each group). (b) Colonic length of rats from four groups. (c) Comparison of colon length among four groups (n = 3 in each group). (d) Spleen index was calculated by dividing the spleen weight (mg) by the corresponding body weight (g) (n = 3 in each group). (e) DAI of four groups (n = 12 in each group). (f) The colon was stained with H&E. (g) Histological scores of colon tissue (n = 3 in each group). (h) Western blot for Claudin-1 from colon mucosa (n = 3 in each group). GAPDH was served as loading control. versus control group; and versus model group; and versus sulfasalazine group.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)