Inhibitory Effect of <i>Phellinus baumii</i> Extract on CFA-Induced Inflammation in MH-S Cells through Nuclear Factor-<i>κ</i>B and Mitogen-Activated Protein Kinase Signaling Pathways

<div>Effect of <i>Phellinus baumii</i> extract (PBE) on coal fly ash (CFA)-stimulated nitric oxide (NO) generation and cell viability in MH-S macrophages. (a) The cells are divided into six groups, namely, the control (basal), CFA only (2.5 <i>μ</i>g/mL), and CFA with PBE (12.5, 25, 50, and 100 <i>μ</i>g/mL) groups. The cells are treated with the abovementioned PBE concentrations for 30 min prior to the CFA treatment and incubated for 18 h. The NO level is determined using the Griess reagent method. (b) The MTT reagent method used to perform the cell viability experiment. A 24-well plate is used to seed the cells. 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transform="matrix(.013,0,0,-0.013,49.366,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,55.606,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,61.846,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> in comparison to the CFA group.</div>

Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: Inhibitory Effect of <i>Phellinus baumii</i> Extract on CFA-Induced Inflammation in MH-S Cells through Nuclear Factor-<i>κ</i>B and Mitogen-Activated Protein Kinase Signaling Pathways 

Figure 1 | Inhibitory Effect of Phellinus baumii Extract on CFA-Induced Inflammation in MH-S Cells through Nuclear Factor-κB and Mitogen-Activated Protein Kinase Signaling Pathways 