Research Article

Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling

Figure 5

Fraxetin inhibits the growth of glioma xenografts in nude mice. (a) Picture of nude mice in control group and fraxetin-treatment group. (b) Tumor volume in control group and fraxetin-treatment group. (c) Picture of tumor in control group and fraxetin-treatment group. (d) Tumor weight of nude mice in control group and fraxetin-treatment group. ((e), (f), and (g)) Western blot analysis of key proteins involved in JAK2/STAT3 signaling in tumor. ((h) and (i)) histological analyses of Ki67 and cleaved caspase 3. ; .
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)
(i)