Research Article
Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
Table 4
Comparison of kidney function of golden hamsters in each group (
±
S).
| | Group | n | 24 h-UP (μg/mL) | Cr (μmol/L) | KI (%) |
| | Control group | 8 | 34.5 ± 6.8 | 16.9 ± 2.2 | 0.3 ± 0.04 | | Model group | 7 | 84.3 ± 3.7 | 494.6 ± 32.6 | 1.4 ± 0.4 | | BBR-H group | 7 | 58.6 ± 4.2 | 217.7 ± 5.83 | 0.5 ± 0.04 | | BBR-L group | 7 | 85.7 ± 7.4 | 337.9 ± 17.1 | 0.7 ± 0.1 | | Irbesartan group | 7 | 25.8 ± 2.3 | 144.8 ± 17.0 | 0.5 ± 0.1 |
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Note. Compared with the control group, ; compared with the model group, . |
