Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway

Table 9

Western blot detection of Nrf2, NLRP3, Caspase-1, and GSDMD protein in golden hamster kidney tissues of each group ( ± S).

Group	Nrf2	NLRP3	Caspase-1	GSDMD
Control group	1.89 ± 0.19	0.11 ± 0.01	0.24 ± 0.09	0.30 ± 0.05
Model group	0.16 ± 0.03	1.23 ± 0.18	1.17 ± 0.05	1.01 ± 0.06
BBR-H group	1.01 ± 0.15	0.58 ± 0.01	0.69 ± 0.14	0.52 ± 0.08
BBR-L group	0.94 ± 0.15	0.81 ± 0.12	0.93 ± 0.10	0.89 ± 0.09
Irbesartan group	0.43 ± 0.07	0.75 ± 0.01	0.82 ± 0.04	0.75 ± 0.09

Note. Compared with the control group, ; compared with the model group, .