Preventive Efficacy and Safety of Yiqi-Wenjing-Fang Granules on Oxaliplatin-Induced Peripheral Neuropathy: A Protocol for a Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

Table 2

Chemotherapy regimen.

Abbreviated name	Components	Dosage	Mode of administration	Treatment course
FOLFOX4	Oxaliplatin	85 mg/m^2	Intravenous infusion for >2 hours on day 1	Every 2 weeks, at least 3 cycles
	Leucovorin	200 mg/m^2	Intravenous infusion for >2 hours on days 1 and 2
	5-Fluorouracil	400 mg/m^2	Intravenous injection on days 1 and 2
		600 mg/m^2	Continuous intravenous infusion for 22 hours on days 1 and 2
mFOLFOX6	Oxaliplatin	85 mg/m^2	Intravenous infusion for >2 hours on day 1	Every 2 weeks, at least 3 cycles
	Leucovorin	400 mg/m^2	Intravenous infusion for >2 hours on day 1
	5-Fluorouracil	400 mg/m^2	Intravenous injection on day 1
		1200 mg/m^2	Continuous intravenous infusion for 22 hours on days 1 and 2
XELOX	Oxaliplatin	130 mg/m^2	Intravenous infusion for >2 hours on day 1	Every 3 weeks, at least 4 cycles
	Capecitabine	1000 mg/m^2	Oral administration twice a day on days 1–14