Research Article
Resveratrol Alleviates Vascular Endothelial Damage Caused by Lower-Extremity Ischemia Reperfusion (I/R) through Regulating Keap1/Nrf2 Signaling-Mediated Oxidative Stress
Figure 3
The protective effect of RSV against HR-treated HUVECs was abolished by knocking down Nrf2. (a) The cell viability of HUVECs treated with different strategies was detected by MTT assay. (b) The apoptotic state of HUVECs treated with different strategies was measured by Hoechst test. (c) The apoptotic rate of HUVECs treated with different strategies was determined by flow cytometry. (d) The expression level of Bcl-2, Bax, and Caspase-3 was detected by Western blot ( vs. control, vs. HR, and vs. RSV + HR).
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