Evidence-Based Complementary and Alternative Medicine / 2021 / Article / Tab 2 / Review Article
Acupuncture Combined with Three-Step Analgesic Drug Therapy for Treatment of Cancer Pain: A Systematic Review and Meta-Analysis of Randomised Clinical Trials Table 2 Risk of bias for the 19 included studies using a modified approach to the Cochrane risk of bias tool.
Risk of bias Trial characteristics Source Random sequence generation Allocation concealment Blinding of participants and personnel Blinding of outcome assessors Infrequent loss to follow-up Free of selective outcome reporting Free of other types of bias Statistical analysis (per protocol, intention to treat, etc.) How is loss to follow-up handled? Adverse event Wang (2018) [10 ] Definitely yes Definitely yes Probably no Probably no Definitely no Definitely no Definitely no Not mentioned Ignored Yes Wang (2016) [11 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Zhong (2016) [12 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely no Probably yes Per protocol Not mentioned No Mi (2010) [13 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Bai (2019) [14 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Liu (2018) [15 ] Definitely yes Definitely yes Probably no Probably no Definitely no Definitely yes Probably yes Not mentioned Ignored Yes Liu (2011) [16 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Fu (2019) [17 ] Definitely yes Definitely yes Probably no Probably no Definitely no Definitely no Definitely no Per protocol Ignored Yes Wu (2019) [18 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely no Probably yes Not mentioned Not mentioned Yes Dong (2018) [19 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Sun (2016) [20 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Zhang (2014) [21 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Per protocol Not mentioned Yes Hui (2019) [22 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Tan (2012) [23 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely no Probably yes Not mentioned Not mentioned Yes Fan (2017) [24 ] Definitely yes Definitely yes Probably no Probably no Definitely yes Definitely yes Probably yes Per protocol Not mentioned No Jiang (2016) [25 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely no Probably yes Per protocol Not mentioned No Li (2017) [26 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned Yes Huang (2018) [27 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Not mentioned Not mentioned No Peng (2012) [28 ] Probably yes Probably yes Probably no Probably no Definitely yes Definitely yes Probably yes Per protocol Not mentioned No
