Research Article

Antioxidant, Cytotoxic, and Antibacterial Activities of the Selected Tibetan Formulations Used in Gandaki Province, Nepal

Table 4

Root length and number of Allium cepa obtained after incubation with ethanolic extracts of the samples and standard drug.

GroupsConcentrationRoot length (cm)
0 (hr)24 (hrs)48 (hrs)72 (hrs)96 (hrs)

ControlDistilled water3 ± 0.29 (n = 10)3.20 ± 0.15 (n = 20)4.20 ± 0.12 (n = 30)4.30 ± 0.06 (n = 38)4.87 ± 0.07 (n = 43)

Basam1 mg/ml2.47 ± 0.29 (n = 13)2.23 ± 0.15 (n = 14)2.07 ± 0.18 (n = 17)1.70 ± 0.15 (n = 18)1.70 ± 0.15 (n = 22)
10 mg/ml2.77 ± 0.15 (n = 12)2.53 ± 0.09 (n = 11)2.20 ± 0.12 (n = 10)2.17 ± 0.09 (n = 8)2 ± 0.12 (n = 7)

Dadue1 mg/ml2.67 ± 0.09 (n = 13)2.67 ± 0.09 (n = 14)2.57 ± 0.07 (n = 16)2.43 ± 0.09 (n = 18)2.33 ± 0.09 (n = 19)
10 mg/ml3 ± 0.29 (n = 14)3 ± 0.29 (n = 13)2.90 ± 0.23 (n = 12)2.70 ± 0.21 (n = 10)2.60 ± 0.15 (n = 9)

Mutik-251 mg/ml2.90 ± 0.49 (n = 14)2.73 ± 0.43 (n = 16)2.73 ± 0.43 (n = 17)2.30 ± 0.44 (n = 20)2.27 ± 0.43 (n = 24)
10 mg/ml2.90 ± 0.35 (n = 14)2.93 ± 0.34 (n = 14)2.57 ± 0.35 (n = 12)2.50 ± 0.29 (n = 10)2.33 ± 0.17 (n = 10)

Serdok-111 mg/ml4.10 ± 0.15 (n = 13)4.73 ± 0.30 (n = 14)4.57 ± 0.15 (n = 16)4.47 ± 0.20 (n = 18)4.37 ± 0.19 (n = 19)
10 mg/ml2.63 ± 0.09 (n = 11)2.57 ± 0.13 (n = 10)2.53 ± 0.17 (n = 9)2.47 ± 0.13 (n = 8)2.37 ± 0.13 (n = 7)

Cyclophosphamide1 mg/ml2.97 ± 0.03 (n = 12)2.97 ± 0.09 (n = 14)2.90 ± 0.12 (n = 14)2.53 ± 0.18 (n = 16)2.40 ± 0.23 (n = 18)
10 mg/ml3.57 ± 0.43 (n = 13)3.30 ± 0.44 (n = 11)3.10 ± 0.44 (n = 10)2.87 ± 0.43 (n = 8)2.67 ± 0.55 (n = 6)

Notes: all experiments were performed with three replicates, and data were expressed as mean ± standard error of the mean. Statistical significance is given for comparison of root length obtained at 24, 48, 72, and 96 hrs with respect to the control (distilled water) , , ; n: root number.