Research Article

Electroacupuncture in the Contralesional Hemisphere Improves Neurological Function Involving GABA in Ischemia–Reperfusion Injury Rats

Table 2

The effect of electroacupuncture on neurological status and infarction volume in ischemia-reperfusion injury rats.

Group
Normal (N  = 12)Sham (N  = 12)EA (N  = 12)

Neurological deficit score
D30.00 (0.00, 0.00)7.00 (7.00, 8.00)7.00 (7.00, 8.00)
D150.00 (0.00, 0.00)7.00 (7.00, 7.00)4.00 (3.00, 4.00)
Day 14–day 30.00 (0.00, 0.00)0.00 (−1.00, 0.00)−4.00 (−4.00, −3.00)

Rotarod test
D385.92 (81.54, 133.56)34.22 (28.31, 42.77)37.52 (32.72, 42.73)
D1591.78 (88.78, 105.34)38.35 (28.97, 42.43)84.10 (76.83, 92.43)
D15–D32.57 (−7.93, 7.78)3.53 (−0.39, 7.48)44.80 (41.69, 54.13)

Passive avoidance test
D3226.40 (33.43, 300.00)300.00 (243.60, 300.00)300.00 (138.90, 300.00)
D15167.00 (16.40, 300.00)49.00 (16.80, 276.93)271.75 (114.68, 300.00)
D15–D3−8.05 (−53.55, 10.05)−168.75 (−275.85, −8.25)−28.25 (−135.43, 0.00)

Infarction volume
Ratio (N = 6)0.00 ± 0.000.19 ± 0.040.07 ± 0.04

Data are represented as median (Q1, Q3) or mean ± standard deviation. Normal: normal group; Sham: sham group; EA: electroacupuncture group; D3: 3rd day after reperfusion; D15 : 15th day after reperfusion; D15–D3: the difference between the 15th day and 3rd day; , , and compared to normal; , , and compared to sham.