Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway

Figure 1

Effects of different concentrations and time points of evodiamine on human AGS and BGC-823 cell cytotoxicity. AGS cells were treated with 1.5625, 3.125, 6.25, 12.5, 25, 50, and 100 μM evodiamine and BGC-823 cells were treated with 0.78, 1.5625, 3.125, 6.25, 12.5, 25, and 50 μM evodiamine for 24, 48, and 72 h. CCK-8 assay was used to detect cell cytotoxicity. (a) Effects of different concentrations and time points of evodiamine on AGS cell cytotoxicity. (b) Effects of different concentrations and time points of evodiamine on BGC-823 cell cytotoxicity. Data were analyzed using one-way ANOVA followed by LSD. All data are presented as the mean ± SD.

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