Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway

Figure 6

Effect of evodiamine on the gene expression level of PTEN-mediated EGF/PI3K signaling pathways. The relative mRNA expression levels of PTEN (a), EGF (b), EGFR (c), AKT (d), mTOR (e), Beclin-1 (f), Bcl-2 (g), Bax (h), caspase-3 (i), and caspase-8 (j) were detected by RT-PCR in different groups. and ^∗∗ versus control group (0 μM). Data were analyzed using one-way ANOVA followed by LSD. All data are presented as the mean ± SD (n = 3).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)