Curcumin Inhibits HGF-Induced EMT by Regulating c-MET-Dependent PI3K/Akt/mTOR Signaling Pathways in Meningioma

Figure 4

Curcumin effectively inhibited hepatocyte growth factor-induced tumor growth and epithelial-mesenchymal transition. (a) Image of tumor size (scale bar: 50 µm). (b) Wet tumor weight at the time of dissection. (c) Immunohistochemistry (IHC) of the expression pattern of E-cadherin and N-cadherin of tumor tissues from the xenograft tumor model (magnification: 400x). Data are expressed as mean ± standard error; n = 4; the asterisk () indicates a significant difference compared to the ctrl group, . The hash (#) indicates a significant difference compared to the HGF group, ^#.

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