The Efficacy of Ozone Prolotherapy Compared to Intra-Articular Hypertonic Saline Injection in Reducing Pain and Improving the Function of Patients with Knee Osteoarthritis: A Randomized Clinical Trial

Table 4

Comparison of WOMAC and subscales between the two groups.

Scale		Hypersaline group (mean ± SD)	Ozone + hypersaline group (mean ± SD)	value within groups	value between groups
WOMAC. pain	Baseline	10.94 ± 2.73	10.85 ± 3.34	<0.001	0.46
	2^nd week	11.73 ± 2.68	13.28 ± 4.84
	4^th week	8.73 ± 3.01	9.42 ± 5.72
WOMAC. stiffness	Baseline	4.05 ± 1.84	3.2 ± 1.72	<0.001	0.65
	2^nd week	4.21 ± 1.75	4.53 ± 2.09
	4^th week	3.15 ± 1.06	3.2 ± 2.04
WOMAC. function	Baseline	36.61 ± 8.69	37.21 ± 42.35	<0.001	0.37
	2^nd week	37.88 ± 11.38	42.35 ± 15.09
	4^th week	28.94 ± 11.44	31.21 ± 17.95
WOMAC. total	Baseline	51.88 ± 9.88	51.28 ± 12.76	<0.001	0.52
	2^nd week	53.83 ± 14.22	60.14 ± 21.42
	4^th week	41.16 ± 11.44	43.92 ± 25.4

WOMAC, Western Ontario McMaster University Osteoarthritis Index.