Spasmolytic Effect of Grewia asiatica Fruit Extract on Isolated Smooth Muscles is Mediated via Multiple Pathways

Figure 1

The graphs presenting the activity of Grewia asiatica 70% methanolic extract (Ga.Cr) on isolated intestinal smooth muscle preparations. The graph on the top shows the effect of Ga.Cr upon baseline rabbit jejunum spasmogenicity. The relaxant activity depicted is the percent of spontaneous contractions of the tissue (results are mean ± SEM for 7 observations). The graph at the bottom shows activity of the extract on high K⁺ (80 mM) spasmogenicity in jejunal and ileal preparations. The spasmolytic behaviour of Ga.Cr is % of agonist-sustained spasmogenicity (results are mean ± SEM for 3 observations).