Spasmolytic Effect of Grewia asiatica Fruit Extract on Isolated Smooth Muscles is Mediated via Multiple Pathways

Figure 3

The graphs representing the activity of different standard spasmolytic agents on isolated rabbit jejunum tissue preparations. The graph on the top shows the effect of increasing concentrations of cromakalim upon resting baseline, K⁺ (80 mM) and K⁺ (25 mM) spasmogenicity, and K⁺ (25 mM) with and without the standard antagonist glibenclamide 3 μM (glib) (results are mean ± SEM for 3–5 observations). The bottom graph showing the effect of verapamil on the resting spontaneous baseline, K⁺ (80 mM), and K⁺ (25 mM) spasmogenicity (results are mean ± SEM for 7–10 observations).