Antifibrotic Effects of Kangxian Ruangan Capsule on Rats with Nonalcoholic Fatty Liver Fibrosis and Hepatic Stellate Cells through Regulation of TGF-β and TLR4 Signaling Pathways

Figure 6

KXRG suppressed proliferation, collagen synthesis, and α-SMA expression in HSCs stimulated by PDGF. (a) Effect of PDGF on HSC proliferation; compared with 0 ng/mL PDGF group; (b) Effect of KXRG on HSC proliferation stimulated by PDGF; (c) Effect of KXRG on collagen synthesis in HSCs stimulated by PDGF; (d) and (e) Effect of KXRG on α-SMA expression of HSCs stimulated by PDGF; compared with 10% FBS group; compared with 10% FBS + 10 ng/mL PDGF group; compared with 10% FBS + 10 ng/mL PDGF + 10 mg/mL KXRG group.

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