Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer’s Disease by Network Pharmacology and Experimental Validation

Table 1

Result of GO functional analysis.

Description	Count	FDR
G-protein-coupled amine receptor activity	17	8.17E − 25
G-protein-coupled peptide receptor activity	21	1.42E − 23
Peptide receptor activity	21	3.43E − 23
G-protein-coupled neurotransmitter receptor	12	6.82E − 18
G-protein-coupled serotonin receptor	11	4.78E − 17
Serotonin receptor activity	11	4.78E − 17
Neurotransmitter receptor activity	15	2.71E − 16
Neuropeptide receptor activity	9	1.32E − 11
Adrenergic receptor activity	6	4.43E − 10
Protein phosphatase binding	11	6.75E − 10
Phosphatase binding	12	9.97E − 10
Catecholamine binding	6	1.37E − 09
Acetylcholine receptor activity	6	3.51E − 09
G-protein alpha-subunit binding	6	4.66E − 09
Neuropeptide binding	6	4.66E − 09
G-protein-coupled receptor binding	13	1.12E − 08
Icosanoid receptor activity	5	1.91E − 08
Protein tyrosine kinase activity	9	1.02E − 07
Protein serine/threonine/tyrosine kinase activity	6	1.93E − 07
Ammonium ion binding	7	3.01E − 07
Prostanoid receptor activity	4	3.74E − 07
Insulin receptor substrate binding	4	3.74E − 07
Phosphatidylinositol phospholipase C	5	3.98E − 07
Phospholipase C activity	5	5.89E − 07
MAP kinase activity	4	1.12E − 06
Bioactive lipid receptor activity	4	1.12E − 06
Peptide binding	11	1.42E − 06
Hormone receptor binding	9	1.56E − 06
Protein serine/threonine kinase activity	13	1.98E − 06
Phosphoprotein binding	6	9.85E − 06