Research Article

Tongxinluo Exerts Inhibitory Effects on Pyroptosis and Amyloid-β Peptide Accumulation after Cerebral Ischemia/Reperfusion in Rats

Figure 2

Caspase-11/GSDMD mediated pyroptosis in astrocytes and intervention effects of TXL. (a–c) Protein levels of pro/cleaved caspase-11 and GSDMD-FL/N in each group; n = 6. Data are presented as mean ± SEM.  < 0.01 versus the sham group. ▲▲ < 0.01 versus the I/R group. (d-e) Representative pictures of double immunofluorescence staining of GFAP (green, the biomarker of astrocytes) with caspase-11/GSDMD (red), respectively; scale bars, 50 μm.