Research Article
[Retracted] LINC00035 Transcriptional Regulation of SLC16A3 via CEBPB Affects Glycolysis and Cell Apoptosis in Ovarian Cancer
Figure 4
The LINC00035/CEBPB/SLC16A3 pathway affects glycolysis and apoptosis in OC cells. (a) CCK-8 assays examined A2780 and SKOV3 cells upon SLC16A3 knockdown or LINC00035 knockdown and SLC16A3 overexpression concurrently. (b, c) Representative view and statistics of A2780 and SKOV3 cells transferring from the apical chamber of the transwell system uncoated or coated with Matrigel into the basolateral chamber upon SLC16A3 knockdown or LINC00035 knockdown and SLC16A3 overexpression concurrently. (d) Immunoblots and quantification of bcl-2 and bax in A2780 and SKOV3 cells upon SLC16A3 knockdown or LINC00035 knockdown and SLC16A3 overexpression concurrently. (e) Glucose uptake, lactate production, and ATP production measurements in A2780 and SKOV3 cells upon SLC16A3 knockdown or LINC00035 knockdown and SLC16A3 overexpression concurrently .
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