Speckle Tracking Echocardiography Verified the Efficacy of Qianyangyuyin Granules in Alleviating Left Ventricular Remodeling in a Hypertensive Rat Model

Figure 8

QYYY granules downregulated cardiac fibrosis and hypertrophy. Comparing with the SHR group, the expression of (a, b) TGF-β and (a, c) p-Smad 3 proteins, which were the key genes induced in the cardiac fibrosis, significantly reduced in the SHR + QH group by western blot. QYYY granules reduced the level of (a, d) MYH7 and (a, e) the rate of MYH7/MYH6 involved in cardiac hypertrophy in the SHR + QH group when compared with the SHR group by western blot. , compared to the WKY group; , compared to the SHR group. n = 4 per group.

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