Speckle Tracking Echocardiography Verified the Efficacy of Qianyangyuyin Granules in Alleviating Left Ventricular Remodeling in a Hypertensive Rat Model

Table 2

Comparison of LV structural and functional parameters among 5 groups.

Group	LVM (g)	LVD (mm)	IVSd (mm)	LVPW (mm)	RWT	LVEF (%)	E (cm/s)	e (cm/s)	E/e
WKY (n = 4)	1.18 ± 0.06	6.68 ± 0.24	1.68 ± 0.19	1.59 ± 0.08	0.50 ± 0.05	79.75 ± 2.99	107.50 ± 10.75	4.00 ± 0.82	27.36 ± 3.32
SHR (n = 4)	1.33 ± 0.12	6.18 ± 0.34	2.32 ± 0.08	1.91 ± 0.12	0.68 ± 0.03	73.75 ± 3.30	97.75 ± 19.62	3.25 ± 0.50	30.73 ± 8.42
SHR + V (n = 4)	1.24 ± 0.02	6.14 ± 0.47	2.07 ± 0.14	1.96 ± 0.05	0.66 ± 0.07	85.50 ± 1.29	81.00 ± 8.83	4.12 ± 0.25	19.69 ± 2.48
SHR + QL (n = 4)	1.24 ± 0.04	6.28 ± 0.47	1.99 ± 0.07	1.73 ± 0.17	0.62 ± 0.07	75.75 ± 1.50	107.50 ± 19.60	3.75 ± 0.96	29.29 ± 4.81
SHR + QH (n = 4)	1.19 ± 0.06	5.71 ± 0.35	1.85 ± 0.05	1.65 ± 0.07	0.61 ± 0.05	83.25 ± 3.30	90.50 ± 19.69	5.50 ± 1.73	17.59 ± 6.01

Values area means ± SD. WKY, Wistar-Kyoto; SHR, spontaneously hypertensive rats; SHR + V, SHR + valsartan; SHR + QL, SHR + QYYY low dose; SHR + QH, SHR + QYYY high dose; LVM, left ventricular mass; LVD, left ventricular internal dimension at end diastole; IVSd, interventricular septal thickness at diastole; LVPW, left ventricular postwall thickness at diastole; RWT, relative wall thickness; LVEF, left ventricular ejection fraction. and , compared to the WKY group; and , compared to the SHR group; , compared to the SHR + V group; and , compared to the SHR + QL group.